Randomized trial · 2000
Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue
E. E. Baulieu, G. Thomas, S. Legrain, N. Lahlou, M. Roger, B. Debuire. Proceedings of the National Academy of Sciences · N=280.
A year of DHEA replacement in older adults moved some hormone markers and skin/libido items. It did not produce a status, cognition, or income story. The optimization-panel favorite remains a biomarker looking for a job.
Open sourcedoi:10.1073/pnas.97.8.4279PMID 10760294
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What Causes What. “Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue.” https://whatcauseswhat.org/papers/p-baulieu-2000 (atlas updated 2026-08-31).