Mendelian randomization · 2021

The causal role of circulating vitamin D concentrations in human complex traits and diseases: a large-scale Mendelian randomization study

X. Jiang, P. F. O'Reilly, H. Aschard. Scientific Reports · N=443734.

138 25(OH)D instruments against 190 GWAS. Multiple sclerosis is the standout exception; anthropometrics and most other complex traits are not. Socioeconomic success is not in the 'caused by D' column.

Open source doi:10.1038/s41598-020-80655-w PMID 33420254

Edges that cite this paper

Genetic instruments for 25(OH)D do not buy you a job. The observational D–success link was a marker.

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What Causes What. “The causal role of circulating vitamin D concentrations in human complex traits and diseases: a large-scale Mendelian randomization study.” https://whatcauseswhat.org/papers/p-jiang-2021 (atlas updated 2026-08-31).

https://whatcauseswhat.org/papers/p-jiang-2021