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What Causes What
Lifestyle & environment

Ultra-processed food intake

% of energy

Diet quality marker. Tracks income, time poverty, and metabolic load.

UPF is both a cause of metabolic damage in feeding trials and a SES symptom. Using it as a moral explanation for other people's hormones skips the budget constraint.

Also called junk food, NOVA 4.

Connected relationships

MECHANISM+ INCREASES

Randomized trial · Moderate

Ultra-processed food intake→Insulin resistance (HOMA-IR)

Higher Ultra-processed food intake increases Insulin resistance (HOMA-IR).

In Hall's ward trial and Hamano's Tokyo crossover, ultra-processed menus matched for presented calories raised ad-lib intake and weight; Chen's US cohorts associate the same food class with later type 2 diabetes, not with measured HOMA-IR.

Read the full evidence

Sources