Table 1

The matrix

While other resources grade individual supplements or habits, this atlas grades the relationships between them. You can filter the table below, and the URL will update so you can easily share your exact view.

ScopeAll

Layer

Biology & endocrinology Psychology & behavior Socioeconomic status Lifestyle & environment

Stamp

Robust causal Genetic causal Feedback loop Spurious / confounded

From	Stamp	Sign	To	Design	N papers
Aerobic	MECHANISM	0 NULL	HOMA-IR	Randomized trial	1
Aerobic	MECHANISM	− DECREASES	Depression	Randomized trial	7
Aerobic	SMOKE	− DECREASES	Mortality	Observational	7
Alcohol	MENDELIAN	0 NULL	Cognition	Mendelian randomization	3
Alcohol	MENDELIAN	+ INCREASES	CV events	Mendelian randomization	5
Alcohol	MENDELIAN	? CONDITIONAL	Depression	Mendelian randomization	3
Alcohol	MENDELIAN	+ INCREASES	Mortality	Mendelian randomization	1
Alcohol	MECHANISM	− DECREASES	Sleep	Review	3
Alcohol	MECHANISM	~ NON-LINEAR	T	Review	4
Air pollution	SMOKE	− DECREASES	Cognition	Observational	2
Air pollution	SMOKE	+ INCREASES	Mortality	Observational	3
Ashwagandha	MECHANISM	− DECREASES	Cortisol	Randomized trial	1
Ashwagandha	MECHANISM	+ INCREASES	Sleep	Randomized trial	2
Ashwagandha	MECHANISM	+ INCREASES	T	Randomized trial	1
Bacopa	MECHANISM	? CONDITIONAL	Cognition	Randomized trial	3
Berberine	MECHANISM	− DECREASES	HOMA-IR	Randomized trial	3
Breastfeeding	SMOKE	+ INCREASES	Cognition	Observational	3
Caffeine	SMOKE	~ NON-LINEAR	Mortality	Meta-analysis	4
Caffeine	MECHANISM	? CONDITIONAL	Sleep	Randomized trial	2
Chamomile	MECHANISM	+ INCREASES	Sleep	Randomized trial	1
Chromium	MECHANISM	− DECREASES	HOMA-IR	Randomized trial	5
Smoking	SMOKE	+ INCREASES	HOMA-IR	Observational	2
CoQ10	MECHANISM	− DECREASES	CV events	Randomized trial	3
Creatine	MECHANISM	? CONDITIONAL	Cognition	Randomized trial	2
Creatine	MECHANISM	? CONDITIONAL	Depression	Randomized trial	1
Creatine	MECHANISM	? CONDITIONAL	Strength	Randomized trial	4
Curcumin	MECHANISM	− DECREASES	Depression	Randomized trial	1
Income	MECHANISM	+ INCREASES	Vitamins	Observational	1
Eating window	MECHANISM	? CONDITIONAL	HOMA-IR	Randomized trial	8
Evening light	MECHANISM	− DECREASES	Sleep	Randomized trial	8
Power pose	SMOKE	0 NULL	Risk	Randomized trial	3
Power pose	SMOKE	0 NULL	T	Randomized trial	4
Fenugreek	MECHANISM	? CONDITIONAL	T	Randomized trial	3
GLP-1	MECHANISM	− DECREASES	Alcohol	Randomized trial	5
GLP-1	MECHANISM	− DECREASES	CV events	Randomized trial	3
GLP-1	MECHANISM	0 NULL	Depression	Randomized trial	2
GLP-1	MECHANISM	+ INCREASES	Fertility	Randomized trial	4
GLP-1	MECHANISM	− DECREASES	HOMA-IR	Randomized trial	4
GLP-1	MECHANISM	− DECREASES	Kidney	Randomized trial	3
GLP-1	MECHANISM	− DECREASES	Mortality	Randomized trial	2
GLP-1	MECHANISM	− DECREASES	OSA	Randomized trial	3
GLP-1	MECHANISM	− DECREASES	Strength	Randomized trial	2
GLP-1	MECHANISM	+ INCREASES	Wellbeing	Randomized trial	2
Green tea	MECHANISM	? CONDITIONAL	Cognition	Randomized trial	2
Green tea	MECHANISM	0 NULL	HOMA-IR	Randomized trial	3
Inositol	MECHANISM	− DECREASES	HOMA-IR	Randomized trial	3
L-theanine	MECHANISM	? CONDITIONAL	Cognition	Randomized trial	6
Lion's mane	MECHANISM	? CONDITIONAL	Cognition	Randomized trial	3
Magnesium	MECHANISM	− DECREASES	Depression	Randomized trial	2
Magnesium	MECHANISM	? CONDITIONAL	HOMA-IR	Randomized trial	5
Magnesium	MECHANISM	+ INCREASES	Sleep	Randomized trial	2
Med diet	MECHANISM	− DECREASES	HOMA-IR	Randomized trial	2
Melatonin	MECHANISM	? CONDITIONAL	Sleep	Randomized trial	2
Shift work	MECHANISM	+ INCREASES	HOMA-IR	Randomized trial	2
Traffic noise	SMOKE	+ INCREASES	CV events	Meta-analysis	3
Traffic noise	SMOKE	− DECREASES	Sleep	Meta-analysis	5
Omega-3	MECHANISM	? CONDITIONAL	CV events	Randomized trial	3
Omega-3	MECHANISM	? CONDITIONAL	Depression	Randomized trial	3
Omega-3	SMOKE	0 NULL	Employment	Observational	1
Probiotic	MECHANISM	− DECREASES	Depression	Randomized trial	3
Sitting	MECHANISM	+ INCREASES	HOMA-IR	Randomized trial	6
Lifting	MECHANISM	− DECREASES	Depression	Randomized trial	1
Lifting	MECHANISM	− DECREASES	HOMA-IR	Randomized trial	2
Lifting	MECHANISM	~ NON-LINEAR	T	Observational	2
Rhodiola	MECHANISM	? CONDITIONAL	Depression	Randomized trial	2
Screens	SMOKE	? CONDITIONAL	Cognition	Observational	2
Sleep	MECHANISM	+ INCREASES	Cognition	Meta-analysis	4
Sleep	MECHANISM	− DECREASES	Cortisol	Randomized trial	2
Sleep	MECHANISM	0 NULL	Depression	Randomized trial	2
Sleep	MECHANISM	− DECREASES	HOMA-IR	Randomized trial	11
Sleep	SMOKE	~ NON-LINEAR	Mortality	Meta-analysis	7
Sleep	MECHANISM	+ INCREASES	T	Randomized trial	5
St John's wort	MECHANISM	0 NULL	Depression	Randomized trial	2
Tart cherry	MECHANISM	? CONDITIONAL	Sleep	Randomized trial	4
Outdoors	MECHANISM	+ INCREASES	25(OH)D	Observational	2
UPF	MECHANISM	+ INCREASES	HOMA-IR	Randomized trial	3
Valerian	MECHANISM	+ INCREASES	Sleep	Randomized trial	3
Vitamins	SMOKE	0 NULL	Employment	Observational	2
Vitamins	MECHANISM	0 NULL	Cognition	Randomized trial	3
Zinc	MECHANISM	? CONDITIONAL	Cognition	Randomized trial	2
Zinc	MECHANISM	+ INCREASES	T	Randomized trial	2

81 edges in this cut

Cite this page

What Causes What. “Effect matrix.” https://whatcauseswhat.org/matrix?layer=lifestyle (atlas updated 2026-09-02).

https://whatcauseswhat.org/matrix?layer=lifestyle

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